Wu Mei Wan - 鳥梅丸

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Wu Mei Wan - 鳥梅丸

This traditional recipe is now obtainable in its original form in contemporary clinics around the globe. It is a tried and true herbal remedy with centuries of successful results in essential health and well-being.

Originally known as a "Honey Pill", at Empirical Health prefer the term "Honey Pearl". This name reflects the dedication of time and effort invested in crafting a distinctive and valuable pearl, in keeping with the traditions of classical texts.



    Simultaneously warm the lower body and drain heat from upper, to treat complex or chronic conditions that may involve parasites, cold extremities, diarrhoea or abdominal pain. This formula is the primary formula for Jue Yin disease.

    Parasitic infestations
    Ulcerative colitis
    Chronic diarrhoea
    Irritable bowel syndrome

    Parasitic infestations with Stomach heat and Intestinal cold.
    Colitis due to Yang deficiency
    Diarrhoea containing pus due to simultaneous pathogenic heat and cold.

    Wu Mei Wan addresses the presence of both pathogenic heat and cold by using a combination of bitter, cooling herbs alongside acrid, warming herbs. Sour herbs are also included for their calming and quietening effect on parasites, as well as on general irritability and disorder.

    Wu Mei Wan has been shown to exhibit anti-inflammatory, antioxidative, and immunomodulatory effects. It may assist in maintaining the epithelial barrier function (gut wall) and improve dysbiosis. There is also preliminary evidence to suggest that Wu Mei Wan inhibits the invasion and metastasis of gastric cancer cells.

    This formula is indicated for a complex disease pattern, with a multitude of possible signs and symptoms. It should be considered when there are signs of cold such as cold extremities, diarrhoea or abdominal pain that responds to warmth, along with simultaneous signs of heat such as irritability, dark urine, thirst, hunger or vomiting after eating.

    In the treatment of parasitic infestations, Wu Mei Wan calms and contains the parasitic activity to reduce unpleasant symptoms. In many cases it will need to be followed by a purgative formula, to expel the parasites and complete the treatment.

    Huang J, Zheng Y, Ma J, Ma J, Lu M, Ma X, Wang F, Tang X. Exploration of the Potential Mechanisms of Wumei Pill for the Treatment of Ulcerative Colitis by Network Pharmacology. Gastroenterol Res Pract. 2021 Dec 21;2021:4227668. doi: 10.1155/2021/4227668. PMID: 34970312; PMCID: PMC8714398.

    Tao M, Wang X, Wang A, Gao N, Pan J, Liu X, Wang X. Effect of jiaweiwumel decoction on regulatory T cells and interleukin-10 in a rat model of ulcerative colitis. J Tradit Chin Med. 2015 Jun;35(3):312-5. doi: 10.1016/s0254-6272(15)30103-5. PMID: 26237836.
    Hours

    Wu X, Chen H, Gao X, Gao H, He Q, Li G, Yao J, Liu Z. Natural Herbal Remedy Wumei Decoction Ameliorates Intestinal Mucosal Inflammation by Inhibiting Th1/Th17 Cell Differentiation and Maintaining Microbial Homeostasis. Inflamm Bowel Dis. 2022 Jan 29:izab348. doi: 10.1093/ibd/izab348. Epub ahead of print. PMID: 35092428.

    Wu X, Chen H, Gao X, Gao H, He Q, Li G, Yao J, Liu Z. Natural Herbal Remedy Wumei Decoction Ameliorates Intestinal Mucosal Inflammation by Inhibiting Th1/Th17 Cell Differentiation and Maintaining Microbial Homeostasis. Inflamm Bowel Dis. 2022 Jan 29:izab348. doi: 10.1093/ibd/izab348. Epub ahead of print. PMID: 35092428.

    Guan Z, Zhao Q, Huang Q, Zhao Z, Zhou H, He Y, Li S, Wan S. Modified Renshen Wumei Decoction Alleviates Intestinal Barrier Destruction in Rats with Diarrhea. J Microbiol Biotechnol. 2021 Sep 28;31(9):1295-1304. doi: 10.4014/jmb.2106.06037. PMID: 34319258.

    Ma NX, Sun W, Wu J, Liu SL, Weng L, Liu YQ, Pu WX, Wu TT, Ding XL, Huang NG, Zheng PQ, Zou X. Compound Wumei Powder Inhibits the Invasion and Metastasis of Gastric Cancer via Cox-2/PGE2-PI3K/AKT/GSK3β/β-Catenin Signaling Pathway. Evid Based Complement Alternat Med. 2017;2017:3039450. doi: 10.1155/2017/3039450. Epub 2017 Nov 21. PMID: 29358963; PMCID: PMC5735682.

    Fructus Mume (Wu Mei)
    Xi Xin**
    Rhizoma Zingiberis (Gan Jiang)
    Rhizoma Coptidis (Huang Lian)
    Radix Angelicae Sinensis (Dang Gui)
    Pao Fu Pian*
    Fructus Zanthoxyli (Hua Jiao)
    Cortex Cinnamomi (Rou Gui)
    Radix Ginseng (Ren Shen)
    Cortex Phellodendri (Huang Bai)
    Oryza sativa (White Rice)
    Mel (Feng Mi)

    * below 0.02mg per pack of total alkaloids

    ** Free of Aristolochic Acid

    * Contains Certified Organic Ingredients

    Modern: Adults: Chew 3 honey pearls with warm water 3 times daily, or as otherwise directed by your health care professional.

    Classical: Take 8-10 pearls before eating 3 x daily increase to 20 pearls, if required. Avoid cold, raw, slimy and malodorous foods.

    Supplement Facts:

    Each bottle contains: 100g / 3.52oz - Approx 160 pearls

    Suitable for Vegetarians, Paleo Friendly

    No artificial colours, flavours or preservatives, yeast, eggs, wheat, gluten, nuts, dairy or animal products.

    • During pregnancy, always consult with a qualified healthcare practitioner before taking herbal medicines and nutritional supplements
    • Always read the label. Use only as directed. If symptoms persist consult your healthcare practitioner.
    • Statements made on this website have not been evaluated by the Food and Drug Administration or the Therapeutic Goods Administration.  These products are not intended to diagnose, treat, cure, or prevent any disease.

    Highest Grade Herbs

    After each individual ingredient has passed our rigourous three tier testing policy, it is then carefully prepared according to the classical texts before forming into our wonderful and unique honey pearls. We are fanatic when it comes to correct species identification, correct dose and administration of these ancient formulas we are reviving for the modern world.

    Traditional Understanding

    Our honey pearls are raw, unique, and based on a 2000 year old preparation method that optimises the absorption of herbal medicine. By making our formulas into Honey Pearls, the active constituents of the ingredients are absorbed slowly and gradually over time, making them highly bioavailable and slow to release. The strength of our formulas is therefore in the delivery. We call this real deal herbalism!  

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