Liu Wei Di Huang Wan - 六味地黄丸

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Liu Wei Di Huang Wan - 六味地黄丸

This traditional recipe is now obtainable in its original form in contemporary clinics around the globe. It is a tried and true herbal remedy with centuries of successful results in essential health and well-being.

 Originally known as a "Honey Pill", at Empirical Health prefer the term "Honey Pearl". This name reflects the dedication of time and effort invested in crafting a distinctive and valuable pearl, in keeping with the traditions of classical texts



    Nourish Liver and Kidney yin, regulate urination.

    Diabetes
    Chronic nephritis
    Hypertension
    Menopausal syndrome
    Osteoporosis

    Urinary dysfunction due to Kidney Yin deficiency
    Night sweats, thirst, or chronic dry throat due to heat arising from Yin deficiency
    Weakness of the lower back or knees due to Kidney Yin deficiency
    Dizziness, blurred vision or tinnitus due to Kidney and Liver Yin deficiency

    Liu Wei Di Huang Wan promotes urination to clear out pathological fluids, while providing cooling and moistening nourishment to the Liver and Kidney Yin. It was originally a paediatric formula but has for a long time been used in adults with chronic disease. Signs of Liver and/or Kidney Yin deficiency include night sweats, sweating from the hands and feet, thirst, dry mouth, dizziness or blurred vison, urinary symptoms, or a weakness in the lower back or legs.

    Studies on diabetic patients have demonstrated Liu Wei Di Huang Wan can stimulate insulin secretion, improve insulin sensitivity and delay insulin resistance. Liu Wei Di Huang Wan is also anti-inflammatory, and shows promising results in osteoporosis treatment through the upregulation of osteoblastic activity.

    This formula is not suitable for patients with digestive symptoms resulting from a weak Spleen, or in the presence of an active external pathogen.
    This formula may also be suitable for men with erectile dysfunction, including spontaneous or nocturnal emissions.

    Chen HH, Wu CT, Tsai YT, Ho CW, Hsieh MC, Lai JN. Liu Wei Di Huang Wan and the Delay of Insulin Use in Patients with Type 2 Diabetes in Taiwan: A Nationwide Study. Evid Based Complement Alternat Med. 2021 Aug 19;2021:1298487. doi: 10.1155/2021/1298487. PMID: 34457016; PMCID: PMC8390129.

    Xia B, Xu B, Sun Y, Xiao L, Pan J, Jin H, Tong P. The effects of Liuwei Dihuang on canonical Wnt/β-catenin signaling pathway in osteoporosis. J Ethnopharmacol. 2014 Apr 11;153(1):133-41. doi: 10.1016/j.jep.2014.01.040. Epub 2014 Feb 12. PMID: 24530448.
    Liu MM, Dong R, Hua Z, Lv NN, Ma Y, Huang GC, Cheng J, Xu HY. Therapeutic potential of Liuwei Dihuang pill against KDM7A and Wnt/β-catenin signaling pathway in diabetic nephropathy-related osteoporosis. Biosci Rep. 2020 Sep 30;40(9):BSR20201778. doi: 10.1042/BSR20201778. PMID: 32914833; PMCID: PMC7502694.

    Wang J, Yao K, Yang X, Liu W, Feng B, Ma J, Du X, Wang P, Xiong X. Chinese patent medicine liu wei di huang wan combined with antihypertensive drugs, a new integrative medicine therapy, for the treatment of essential hypertension: a systematic review of randomized controlled trials. Evid Based Complement Alternat Med. 2012;2012:714805. doi: 10.1155/2012/714805. Epub 2012 Nov 11. PMID: 23258998; PMCID: PMC3520441.

    Radix Rehmanniae Preparatum (Shu Di Huang)
    Fructus Corni (Shan Zhu Yu)
    Rhizoma Diosscoreae (Shan Yao)
    Rhizoma Alismatis (Ze Xie)
    Poria (Fu Ling)
    Cortex Moutan (Mu Dan Pi)
    Mel (Feng Mi)

    * Contains Certified Organic Ingredients

    Adults: Chew 3 honey pearls with warm water 3 times daily, or as otherwise directed by your health care professional.

    Supplement Facts

    Each bottle contains: 100g / 3.52oz - Approx 160 pearls

    Suitable for Vegetarians, Paleo Friendly

    No artificial colours, flavours or preservatives, yeast, eggs, wheat, gluten, nuts, dairy or animal products.

    • During pregnancy, always consult with a qualified healthcare practitioner before taking herbal medicines and nutritional supplements
    • Always read the label. Use only as directed. If symptoms persist consult your healthcare practitioner.
    • Statements made on this website have not been evaluated by the Food and Drug Administration or the Therapeutic Goods Administration.  These products are not intended to diagnose, treat, cure, or prevent any disease.

    Highest Grade Herbs

    After each individual ingredient has passed our rigourous three tier testing policy, it is then carefully prepared according to the classical texts before forming into our wonderful and unique honey pearls. We are fanatic when it comes to correct species identification, correct dose and administration of these ancient formulas we are reviving for the modern world.

    Traditional Understanding

    Our honey pearls are raw, unique, and based on a 2000 year old preparation method that optimises the absorption of herbal medicine. By making our formulas into Honey Pearls, the active constituents of the ingredients are absorbed slowly and gradually over time, making them highly bioavailable and slow to release. The strength of our formulas is therefore in the delivery. We call this real deal herbalism!  

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