Bie Jia Jian Wan - 鳖甲煎丸

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Bie Jia Jian Wan - 鳖甲煎丸

This traditional recipe is now obtainable in its original form in contemporary clinics around the globe. It is a tried and true herbal remedy with centuries of successful results in essential health and well-being.

Originally known as a "Honey Pill", at Empirical Health prefer the term "Honey Pearl". This name reflects the dedication of time and effort invested in crafting a distinctive and valuable pearl, in keeping with the traditions of classical texts.


Invigorate the Blood and Qi, to eliminate accumulations of Blood stasis and Phlegm and soften and resolve hard masses.

Abdominal masses due to Qi, Blood and Phlegm stagnation.
Enlarged liver or spleen due to Qi, Blood and Phlegm stagnation

Bie Jia Jian Wan is traditionally indicated for malaria-like or Shaoyang symptoms, such as alternating chills and fever and diarrhoea or vomiting which do not resolve with treatment, and progress to the presence of hard masses or tumours, with possible emaciation, pain and jaundice. It is a warming and salty, stasis-melting formula.

Numerous studies have demonstrated the anti-cancer effects of Bie Jia Jian Wan, especially in regard to hepatocellular carcinoma (HCC). It has been shown to repress the proliferation, metastasis and infiltration of HCC cells, exert direct cytotoxic effects, and promote the beneficial infiltration of CD8+T cells into the tumour.

Sun J, Chen W, Wen B, Zhang M, Sun H, Yang X, Zhao W, La L, An H, Pang J, Gao L, He S. Biejiajian Pill Inhibits Carcinogenesis and Metastasis via the Akt/GSK-3β/Snail Signaling Pathway in Hepatocellular Carcinoma. Front Pharmacol. 2021 Mar 8;12:610158. doi: 10.3389/fphar.2021.610158. PMID: 33762939; PMCID: PMC7982731.

Yang X, Sun J, Wen B, Wang Y, Zhang M, Chen W, Zhao W, He C, Zhong X, Liu Y, Li T, Sun H, He S. Biejiajian Pill Promotes the Infiltration of CD8+ T Cells in Hepatocellular Carcinoma by Regulating the Expression of CCL5. Front Pharmacol. 2021 Nov 26;12:771046. doi: 10.3389/fphar.2021.771046. PMID: 34899325; PMCID: PMC8661106.

Jingjing H, Hongna H, Xiaojiao W, Yan G, Yuexue Z, Yueqiang H. Bie Jia Jian pill enhances the amelioration of bone mesenchymal stem cells on hepatocellular carcinoma progression. J Nat Med. 2022 Jan;76(1):49-58. doi: 10.1007/s11418-021-01548-4. Epub 2021 Jul 23. PMID: 34297271; PMCID: PMC8732910.


JGYL Chapter 4 Line 2: Question: Malaria that erupts on the first of each month should subside by the fifteenth day. If not, it should resolve by the end of the month. If the patient does not recover, what should we call this disease? The Master says: This means that the disease is binding into concretions or conglomerations. It is called mother of malaria. Treat this urgently. Bie Jia Jian Wan is appropriate.

Carapax Trionycis (Bie Jia)
Rhizoma Belamcanda (Wu Shan)
Radix Scutellariae (Huang Qin)
Radix Bupleuri (Chai Hu)
Armadillidium (Shu Fu)
Rhizoma Zingiberis (Gan Jiang)
Radix et Rhizoma Rhei (Da Huang)
Radix Paeoniae Rubra (Chi Shao)
Cortex Cinnamomi (Rou Gui)
Semen Lepidii (Ting Li ZI)
Folium Pyrrosiae (Shi Wei)
Cortex Magnoliae Officinalis (Hou Po)
Cortex Moutan (Mu Dan Pi)
Herba Dianthi (Qu Mai)
Folium Pyrrosiae (Ze Wei)
Rhizoma Pinelliae (Ban Xia)
Radix Ginseng (Ren Shen (Bai))
Eupolyphaga seu Steleophaga (Tu Bie Chong)
Colla Corii Asini (E Jiao)
Nidus Vespae (Feng Fang)
Nitrum Rubrum (Chi Xiao)
Catharsius (Qiang Lang)
Semen Persicae (Tao Ren)
Mel (Feng Mi)

* Contains Certified Organic Ingredients

Modern > Adults: Chew 3 honey pearls with warm water 3 times daily, or as otherwise directed by your health care professional.

Classical > Take seven pearls on an empty stomach, three times a day.

Supplement Facts
Each bottle contains: 50g / 1.76oz - Approx. 80 pearls
Paleo Friendly No artificial colours, flavours or preservatives, yeast, eggs, wheat, gluten, nuts, dairy.

  • During pregnancy, always consult with a qualified healthcare practitioner before taking herbal medicines and nutritional supplements
  • Always read the label. Use only as directed. If symptoms persist consult your healthcare practitioner.
  • Statements made on this website have not been evaluated by the Food and Drug Administration or the Therapeutic Goods Administration.  These products are not intended to diagnose, treat, cure, or prevent any disease.

Highest Grade Herbs

After each individual ingredient has passed our rigourous three tier testing policy, it is then carefully prepared according to the classical texts before forming into our wonderful and unique honey pearls. We are fanatic when it comes to correct species identification, correct dose and administration of these ancient formulas we are reviving for the modern world.

Traditional Understanding

Our honey pearls are raw, unique, and based on a 2000 year old preparation method that optimises the absorption of herbal medicine. By making our formulas into Honey Pearls, the active constituents of the ingredients are absorbed slowly and gradually over time, making them highly bioavailable and slow to release. The strength of our formulas is therefore in the delivery. We call this real deal herbalism!  

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