Zhi Bai Di Huang Wan - 知柏地黄丸

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Zhi Bai Di Huang Wan - 知柏地黄丸

This traditional recipe is now obtainable in its original form in contemporary clinics around the globe. It is a tried and true herbal remedy with centuries of successful results in essential health and well-being.

Originally known as a "Honey Pill", at Empirical Health prefer the term "Honey Pearl". This name reflects the dedication of time and effort invested in crafting a distinctive and valuable pearl, in keeping with the traditions of classical texts.

Nourish the Liver and Kidney Yin and clear heat from deficiency, to simultaneously moisten and cool the body, or clear lower burner damp-heat.

Menopausal syndrome with pronounced heat signs.
SLE (Lupus)
Hyperthyroid
Diabetes
Thrush or vaginitis

Menopausal hot flushes due to Kidney Yin-deficiency-heat.
Thrush or vaginitis due to due to damp-heat in the Lower Jiao
Night sweats, thirst, or chronic dry throat due to heat arising from Yin deficiency

Zhi Bai Di Huang Wan acts to promote urination, clear out pathological damp-heat and nourish the Liver and Kidney Yin. Signs of Liver and/or Kidney Yin deficiency include night sweats, sweating from the hands and feet, thirst, dry mouth, dizziness or blurred vison, urinary symptoms, or a weakness in the lower back or legs, and this formula is most appropriate when heat is pronounced.

Studies on diabetic patients have demonstrated Liu Wei Di Huang Wan (base formula) can stimulate insulin secretion, improve insulin sensitivity and delay insulin resistance. Zhi Bai Di Huang Wan is also anti-inflammatory and anti-apoptotic and may support kidney function in cases of acute renal injury.

Yang Z, Xie RF, Zhong MH, Xie GQ, Fan YS, Zhao T. Potential Molecular Mechanisms of Zhibai Dihuang Wan in Systemic Lupus Erythematosus Based on Network Biology. Evid Based Complement Alternat Med. 2020 Apr 13;2020:7842179. doi: 10.1155/2020/7842179. PMID: 32351603; PMCID: PMC7178533.

Hsu YH, Chen TH, Wu MY, Lin YF, Chen WL, Cheng TH, Chen CH. Protective effects of Zhibai Dihuang Wan on renal tubular cells affected with gentamicin-induced apoptosis. J Ethnopharmacol. 2014;151(1):635-42. doi: 10.1016/j.jep.2013.11.031. Epub 2013 Nov 21. PMID: 24269250.

Chen HH, Wu CT, Tsai YT, Ho CW, Hsieh MC, Lai JN. Liu Wei Di Huang Wan and the Delay of Insulin Use in Patients with Type 2 Diabetes in Taiwan: A Nationwide Study. Evid Based Complement Alternat Med. 2021 Aug 19;2021:1298487. doi: 10.1155/2021/1298487. PMID: 34457016; PMCID: PMC8390129.

Radix Rehmanniae (Gan Di Huang)
Fructus Corni (Shan Zhu Yu)
Rhizoma Diosscoreae (Shan Yao)
Rhizoma Alismatis (Ze Xie)
Poria (Fu Ling)
Cortex Moutan (Mu Dan Pi)
Rhizoma Anemarrhenae (Zhi Mu)
Cortex Phellodendri (Huang Bai)
Mel (Feng Mi)

* Contains Certified Organic Ingredients

Adults: Chew 3 honey pearls with warm water 3 times daily, or as otherwise directed by your health care professional.

Each bottle contains: 100g / 3.52oz - Approx 160 pearls

Suitable for Vegetarians, Paleo Friendly

No artificial colours, flavours or preservatives, yeast, eggs, wheat, gluten, nuts, dairy or animal products.

  • During pregnancy, always consult with a qualified healthcare practitioner before taking herbal medicines and nutritional supplements
  • Always read the label. Use only as directed. If symptoms persist consult your healthcare practitioner.
  • Statements made on this website have not been evaluated by the Food and Drug Administration or the Therapeutic Goods Administration.  These products are not intended to diagnose, treat, cure, or prevent any disease.

Highest Grade Herbs

After each individual ingredient has passed our rigourous three tier testing policy, it is then carefully prepared according to the classical texts before forming into our wonderful and unique honey pearls. We are fanatic when it comes to correct species identification, correct dose and administration of these ancient formulas we are reviving for the modern world.

Traditional Understanding

Our honey pearls are raw, unique, and based on a 2000 year old preparation method that optimises the absorption of herbal medicine. By making our formulas into Honey Pearls, the active constituents of the ingredients are absorbed slowly and gradually over time, making them highly bioavailable and slow to release. The strength of our formulas is therefore in the delivery. We call this real deal herbalism!  

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