Ma Zi Ren Wan - 160 HONEY PEARLS / 100 GRAMS


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Ma Zi Ren Wan -麻子仁丸

This traditional recipe is now obtainable in its original form in contemporary clinics around the globe. It is a tried and true herbal remedy with centuries of successful results in essential health and well-being.

Originally known as a "Honey Pill", at Empirical Health prefer the term "Honey Pearl". This name reflects the dedication of time and effort invested in crafting a distinctive and valuable pearl, in keeping with the traditions of classical texts.

Clear internal heat, moisten the intestines, promote the movement of Qi and descend Yangming to unblock the bowels.

Constipation in the weak or elderly
Chronic constipation
Post-partum constipation
Post-surgical constipation

Constipation due to dryness of the Stomach and Intestines.

A Ma Zi Ren Wan pattern is one of ‘Spleen constraint’, whereby the Spleen is unable to distribute fluids, and dryness and heat in the stomach and intestines result. Hard stool with mild abdominal discomfort and frequent urination are hallmark symptoms, as the water is redirected to the Bladder. Ma Zi Ren Wan is not a strong purgative, rather a gentle moistening formula that corrects a Middle Jiao dysfunction.

Research has shown that the active components of Ma Zi Ren Wan can enhance colonic motility, possibly by acting on multiple targets and pathways. It is well tolerated and effective for functional constipation, and in cancer patients with constipation.

In this pattern, the tongue may be dry or with a slightly yellow coat, and the pulse either submerged and rapid, or floating and choppy – the former reflecting interior heat and the latter, external pathogenic dryness resulting in fluid stagnation.

Huang T, Ning Z, Hu D, Zhang M, Zhao L, Lin C, Zhong LLD, Yang Z, Xu H, Bian Z. Uncovering the Mechanisms of Chinese Herbal Medicine (MaZiRenWan) for Functional Constipation by Focused Network Pharmacology Approach. Front Pharmacol. 2018 Mar 26;9:270. doi: 10.3389/fphar.2018.00270. PMID: 29632490; PMCID: PMC5879454.

Yang M, Feng Y, Zhang YL, Smith CM, Hou YN, Wang H, Deng G, Mao JJ. Herbal formula MaZiRenWan (Hemp Seed Pill) for constipation: A systematic review with meta-analysis. Phytomedicine. 2021 Feb;82:153459. doi: 10.1016/j.phymed.2021.153459. Epub 2021 Jan 5. PMID: 33486266.

Zhong LLD, Cheng CW, Kun W, Dai L, Hu DD, Ning ZW, Xiao HT, Lin CY, Zhao L, Huang T, Tian K, Chan KH, Lam TW, Chen XR, Wong CT, Li M, Lu AP, Wu JCY, Bian ZX. Efficacy of MaZiRenWan, a Chinese Herbal Medicine, in Patients With Functional Constipation in a Randomized Controlled Trial. Clin Gastroenterol Hepatol. 2019 Jun;17(7):1303-1310.e18. doi: 10.1016/j.cgh.2018.04.005. Epub 2018 Apr 12. PMID: 29654915.

Huang T, Zhao L, Lin CY, Lu L, Ning ZW, Hu DD, Zhong LLD, Yang ZJ, Bian ZX. Chinese Herbal Medicine (MaZiRenWan) Improves Bowel Movement in Functional Constipation Through Down-Regulating Oleamide. Front Pharmacol. 2020 Jan 23;10:1570. doi: 10.3389/fphar.2019.01570. PMID: 32038247; PMCID: PMC6989537.

Cheng CW, Mok HF, Yau CWS, Chan JTM, Kang YC, Lam PY, Zhong LLD, Zhao C, Ng BFL, Kwok AOL, Tse DMW, Bian ZX. A pilot randomized placebo-controlled study on modified MaZiRenWan: a formulated Chinese medicine to relieve constipation for palliative cancer patients. Chin Med. 2022 Mar 2;17(1):31. doi: 10.1186/s13020-022-00580-0. PMID: 35236375; PMCID: PMC8889635.

Hemp Seed (Huo Ma Ren)
Radix Paeoniae Rubra (Chi Shao)
Fructus Aurantii Immaturus (Zhi Shi)
Radix et Rhizoma Rhei (Da Huang)
Cortex Magnoliae Officinalis (Hou Po)
Semen Armeniacae Amarum (Xing Ren)
Mel (Feng Mi)

* Contains Certified Organic Ingredients

Modern: Adults: Chew 3 honey pearls with warm water 3 times daily, or as otherwise directed by your health care professional.

Classical: Simply chew 10 pearls with warm water 3 x daily until intended effect is noticed. Dose may be gradually decreased over time.

Supplement Facts

Each bottle contains: 100g / 3.52oz - Approx 160 pearls

Suitable for Vegetarians, Paleo Friendly

No artificial colours, flavours or preservatives, yeast, eggs, wheat, gluten, nuts, dairy or animal products.

  • During pregnancy, always consult with a qualified healthcare practitioner before taking herbal medicines and nutritional supplements
  • Always read the label. Use only as directed. If symptoms persist consult your healthcare practitioner.
  • Statements made on this website have not been evaluated by the Food and Drug Administration or the Therapeutic Goods Administration.  These products are not intended to diagnose, treat, cure, or prevent any disease.

Highest Grade Herbs

After each individual ingredient has passed our rigourous three tier testing policy, it is then carefully prepared according to the classical texts before forming into our wonderful and unique honey pearls. We are fanatic when it comes to correct species identification, correct dose and administration of these ancient formulas we are reviving for the modern world.

Traditional Understanding

Our honey pearls are raw, unique, and based on a 2000 year old preparation method that optimises the absorption of herbal medicine. By making our formulas into Honey Pearls, the active constituents of the ingredients are absorbed slowly and gradually over time, making them highly bioavailable and slow to release. The strength of our formulas is therefore in the delivery. We call this real deal herbalism!  


Professional, passionate and experienced.

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