Fu Zi Li Zhong Wan - 附子理中丸

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Fu Zi Li Zhong Wan - 附子理中丸

This traditional recipe is now obtainable in its original form in contemporary clinics around the globe. It is a tried and true herbal remedy with centuries of successful results in essential health and well-being.

Originally known as a "Honey Pill", at Empirical Health prefer the term "Honey Pearl". This name reflects the dedication of time and effort invested in crafting a distinctive and valuable pearl, in keeping with the traditions of classical texts.


Warm the Yang, dispel cold, boost Qi and strengthen the Spleen, to strongly warm the body and improve digestion.
Chronic diarrhoea
Cold body and limbs
Poor digestion
Abdominal Pain

Chronic diarrhoea due to Spleen and Kidney Yang deficiency
Severe abdominal pain due to Spleen and Kidney Yang deficiency
General weakness and fatigue due to Spleen and Kidney Yang deficiency
Chronic or recurrent mouth ulcers due to cold from Spleen and Stomach deficiency

Fu Zi Li Zhong Wan is Li Zhong Wan plus Fu Zi. Li Zhong Wan is used for Tai Yin Spleen Yang deficiency, and with the addition of Fu Zi, is appropriate for a more advanced, and often more severe combined Tai Yin and (Spleen) and Shao Yin (Kidney) Yang deficiency. Fu Zi is strongly warming and tonifying of the Yang.

Fu Zi Li Zhong Wan has been shown to influence Ghrelin, a peptide that plays multiple roles in thermogenesis. In a study on rats with hypothermia, hypothyroid and indigestion, use of Fu Zi Ling Zhong Wan alongside a higher intake of fat, regulated both Ghrelin release and thyroid hormones.
Li Zhong Wan alone has demonstrated an increase in the levels of antioxidant enzymes in gastric tissue, has an anti-inflammatory effect, and may also play a role in ameliorating the gut wall.

Zhao X, Yang S, Zhang W, Zu C, Tang B, Zhang B, Li G, Su L, Cai D. Fuzi-Lizhong pill compensates hypothyroid-hypothermia via ghrelin release. J Ethnopharmacol. 2013 Oct 7;149(3):707-12. doi: 10.1016/j.jep.2013.07.031. Epub 2013 Aug 3. PMID: 23920247.

Zhao X, Wang Y, Yang S, Zhang W, Zu C, Zhang T, Tang B, Zhang B, Li G, Deng B, Cai D. Underlying mechanism of aconitum lizhong acting on experimental hypothermia with indigestion in rats: role of ghrelin. Evid Based Complement Alternat Med. 2012;2012:542461. doi: 10.1155/2012/542461. Epub 2012 Jul 31. PMID: 22899955; PMCID: PMC3415136.

Song H, Hou X, Zeng M, Chen X, Chen X, Yang T, Xu F, Peng J, Peng Q, Cai X, Yu R. Traditional Chinese Medicine Li-Zhong-Tang accelerates the healing of indomethacin-induced gastric ulcers in rats by affecting TLR-2/MyD88 signaling pathway. J Ethnopharmacol. 2020 Sep 15;259:112979. doi: 10.1016/j.jep.2020.112979. Epub 2020 May 19. PMID: 32442585.

Shen Y, Zou J, Chen M, Zhang Z, Liu C, Jiang S, Qian D, Duan JA. Protective effects of Lizhong decoction on ulcerative colitis in mice by suppressing inflammation and ameliorating gut barrier. J Ethnopharmacol. 2020 Sep 15;259:112919. doi: 10.1016/j.jep.2020.112919. Epub 2020 Apr 30. PMID: 32360800.

Shin IS, Lee MY, Lim HS, Seo CS, Ha HK, Shin HK. Gastroprotective effects of Leejung-tang, an oriental traditional herbal formula, on ethanol-induced acute gastric injury in rats. Afr J Tradit Complement Altern Med. 2012 Dec 31;10(2):324-30. doi: 10.4314/ajtcam.v10i2.18. PMID: 24146457; PMCID: PMC3746580.

Radix Ginseng (Ren Shen (Bai))
Rhizoma Atractylodis Macrocephalae (Bai Zhu)
Rhizoma Zingiberis (Gan Jiang)
Radix Glycyrrhizae Preparatum (Zhi Gan Cao)
Pao Fu Pian*
Mel (Feng Mi)

* below 0.02mg per pack of total alkoloids

* Contains Certified Organic Ingredients

Modern: Adults: Chew 3 honey pearls with warm water 3 times daily, or as otherwise directed by your health care professional.

Classical: Honey Pearls crushed and steeped in hot water

Each bottle contains: 100g / 3.52oz - Approx 160 pearls

Suitable for Vegetarians, Paleo Friendly

No artificial colours, flavours or preservatives, yeast, eggs, wheat, gluten, nuts, dairy or animal products.

  • During pregnancy, always consult with a qualified healthcare practitioner before taking herbal medicines and nutritional supplements
  • Always read the label. Use only as directed. If symptoms persist consult your healthcare practitioner.
  • Statements made on this website have not been evaluated by the Food and Drug Administration or the Therapeutic Goods Administration.  These products are not intended to diagnose, treat, cure, or prevent any disease.

Highest Grade Herbs

After each individual ingredient has passed our rigourous three tier testing policy, it is then carefully prepared according to the classical texts before forming into our wonderful and unique honey pearls. We are fanatic when it comes to correct species identification, correct dose and administration of these ancient formulas we are reviving for the modern world.

Traditional Understanding

Our honey pearls are raw, unique, and based on a 2000 year old preparation method that optimises the absorption of herbal medicine. By making our formulas into Honey Pearls, the active constituents of the ingredients are absorbed slowly and gradually over time, making them highly bioavailable and slow to release. The strength of our formulas is therefore in the delivery. We call this real deal herbalism!  

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